Search on: GUANINE NUCLEOTIDE-RELEASING FACTOR 2 
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Descriptor English:   Guanine Nucleotide-Releasing Factor 2 
Descriptor Spanish:   Factor 2 Liberador de Guanina Nucleótido 
Descriptor Portuguese:   Fator 2 de Liberação do Nucleotídeo Guanina 
Synonyms English:   GRF-2
GRF2 Protein, Mammalian
RAP1GRF1
GRF 2
C3G Protein
Guanine Nucleotide Exchange Factor C3G
GRF2
GRF2 Protein  
Tree Number:   D12.644.360.325.300.300
D12.776.476.325.300.300
Definition English:   A 145-kDa guanine nucleotide exchange factor that is specific for rap1 and ras GTP-BINDING PROTEINS. It associates with SH3 domains of the crk family of signaling proteins. 
History Note English:   2000; use GUANINE NUCLEOTIDE EXCHANGE FACTORS (NM) 1997-1999 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   34491 
Unique Identifier:   D020735 

Occurrence in VHL:
 

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